Diuretics

What are diuretics?

Diuretics (sometimes called ‘water pills’) are drugs including furosemide, chlorothiazide and hydrochlorothiazide. Their purpose is to remove excess water from the body although each type of diuretic does this in a different way.

Medical uses of diuretics

Diuretics are used in the treatment of a number of medical conditions including:

• hypertension (high blood pressure); • oedema (fluid retention, swelling or bloating); • cardiac failure; • liver cirrhosis (replacement of liver cells with fibrous scar tissue, as a result of liver disease).

Effects on performance

Diuretics are not used to enhance performance. If anything they have a detrimental effect on performance as they cause dehydration. Diuretics are used for two reasons. Firstly to loose weight rapidly in sports which require the athlete to be within a set weight limit (for example boxers and jockeys). Secondly, to dilute the presence of illegal substances and aid their excretion.

Side-effects of diuretics

The side effects of diuretics are:

• dehydration; • hypotension (low blood pressure); • muscle cramps; • electrolyte disturbances (alterations in the levels of electrolytes such as sodium, potassium and chloride); • muscle weakness; • seizures (or fits/convulsions); • gout (caused by a build-up of uric acid); • fatigue.

Other masking agents

S0. Non-approved substances

S1. Anabolic agents

Anabolic androgenic steroids

Other anabolic agents

S2. Peptide hormones, growth factors and related substances

Erythropoietin

Chorionic gonadotrophin

Corticotrophin

Human growth hormone

Insulin-like growth factor

S3. Beta-2 agonists

S4. Hormone and metabolic modulators

S5. Diuretics and other masking agents 

M1. Manipulation of blood and blood components 

M2. Chemical and physical manipulation

M3. Gene doping

Substances and methods prohibited at all times 

Substances and methods prohibited in-competition

Substances prohibited in particular sports